ABSTRACT
No abstract available.
Subject(s)
Humans , Dermatitis , Immunoglobulins , Lung Neoplasms , Lung , T-LymphocytesABSTRACT
No abstract available.
Subject(s)
Child , Humans , Colitis, Ulcerative , Ulcer , Vasculitis, Leukocytoclastic, CutaneousABSTRACT
Mycobacterium massiliense which is recognized as a separate species from M. abscessus is little known regarding its clinical patterns and the response to treatment. We present a case of a localized cutaneous infection due to M. massiliense of the sole associated with acupuncture. M. massiliense was identified via polymerase chain reaction-hybridization analysis. We treated the patient with single-drug therapy consisting of clarithromycin for 4 months and the patient showed a significant response to this treatment.
Subject(s)
Humans , Acupuncture , Clarithromycin , Foot , MycobacteriumABSTRACT
BACKGROUND: Staphylococcus aureus (SA) has peculiar abilities to colonize the skin in atopic dermatitis (AD) patients. OBJECTIVE: We sought to determine the colonization rates of SA in acute and chronic skin lesions of AD patients, to find any difference in colonization rates according to age and to find the influences of total immunoglobulin E (IgE) and eosinophil counts to the colonization of SA. METHODS: We evaluated the total IgE level and eosinophil counts, and cultured SA from the skin lesions of 687 AD patients (131 acute and 556 chronic skin lesions) and 247 control urticaria patients (July 2009 to November 2010; Samsung Medical Center Dermatology Clinic, Seoul, Korea). RESULTS: The SA colonization rates were 74%, 38% and 3% in acute, chronic skin lesions and control skin, respectively, and they were increased with age in AD patients. The colonization rate in chronic skin lesions was higher in the high IgE/eosinophilia groups as compared to the normal IgE/eosinophil groups. CONCLUSION: The SA colonization rate was higher in AD patients and especially in acute lesions, and had a tendency to increase with age. As the colonization rates were only higher in the high IgE/eosinophilia groups of chronic skin lesions, we suggested that SA may invade the skin through barrier defects in acute skin lesions, but the colonization in chronic lesions may be orchestrated through many different factors.
Subject(s)
Humans , Colon , Dermatitis, Atopic , Dermatology , Eosinophils , Immunoglobulin E , Immunoglobulins , Skin , Staphylococcus aureus , Staphylococcus , UrticariaABSTRACT
BACKGROUND: Recent studies have suggested that obesity, hyperlipidemia, ischemic heart diseases, metabolic syndrome and hypertension can combine with psoriasis. However, the metabolic comorbidities have not been clearly demonstrated in Korean psoriasis patients. OBJECTIVE: The purpose of this study was to analyze the association between psoriasis and metabolic abnormalities including obesity, glucose intolerance, hypertension and dyslipidemia in our center. Treatment response of cyclosporine between a high body mass index (BMI) group and normal BMI group was also analyzed to investigate how obesity may affect psoriasis treatment. METHODS: A retrospective observational study was made on the obesity and metabolic status of psoriasis patients versus normal control group through electronic medical records from January 2008 to April 2009 at Department of Dermatology, Samsung Medical Center, (Seoul, Korea). Medical records, demographics and the Psoriasis Area and Severity Index score before and after cyclosporine treatment were analyzed. RESULTS: There were no significant differences in the metabolic status between normal control and psoriasis patients. Also, there was no significant difference in the treatment response between high BMI group and normal BMI group, after 4 weeks and 8 weeks of cyclosporine treatment. CONCLUSION: Our study suggests that in Korean patients, an association between psoriasis and metabolic abnormalities is not obvious. This may reflect a different severity of obesity and metabolic abnormalities between Western and Asian populations.
Subject(s)
Humans , Asian People , Body Mass Index , Comorbidity , Cyclosporine , Demography , Dermatology , Dyslipidemias , Electronic Health Records , Glucose Intolerance , Hyperlipidemias , Hypertension , Medical Records , Myocardial Ischemia , Obesity , Psoriasis , Retrospective StudiesABSTRACT
No abstract available.
Subject(s)
Benzamides , Drug Eruptions , Mesylates , Piperazines , Pyrimidines , Imatinib MesylateABSTRACT
Lichen sclerosus et atrophicus (LSA) is an inflammatory disease that primarily causes anogenital lesion in middle aged women. We present here a case of facial LSA with an asymptomatic, well-demarcated, whitish to bluish, atrophic patch in a linear pattern on the forehead of a 48-year-old woman. This case showed an atypical clinical presentation and it mimicked en coup de sabre, but the histopathologic results confirmed the diagnosis of LSA.
Subject(s)
Female , Humans , Middle Aged , Forehead , Lichen Sclerosus et Atrophicus , Lichens , Scleroderma, LocalizedABSTRACT
BACKGROUND: Few clinical studies are available on childhood and adolescent psoriasis in Korea. OBJECTIVE: The purpose of this study was to analyze clinical features of childhood and adolescent psoriasis in a referral center in Korea. METHODS: We performed retrospective medical record-based analyses for 255 psoriasis patients younger than 16 years of age at the time of diagnosis at our center from March 2001 to July 2010. Age, sex, onset age, familial history, site of involvement, type of psoriasis, nail involvement, initial PASI score, and treatment modality were analyzed. RESULTS: There was no sexual predominance; mean age of onset was 8.85 years; 17.25% of patients had a familial history. Upper extremities, lower extremities, trunk, scalp and face were the most commonly involved sites in sequence. Guttate psoriasis (58.90%) was the most common type of psoriasis. Nail involvement was observed in 11.11% of patients. The mean initial PASI score at the time of diagnosis was 7.9. The most common treatment was topical steroids and topical vitamin D in combination. CONCLUSION: Childhood and adolescent psoriasis is not an uncommon disease. A larger scale epidemiological study is needed.
Subject(s)
Adolescent , Humans , Age of Onset , Epidemiologic Studies , Lower Extremity , Nails , Psoriasis , Referral and Consultation , Retrospective Studies , Scalp , Steroids , Upper Extremity , Vitamin DABSTRACT
Palisaded encapsulated neuroma (PEN) is a benign cutaneous neural tumor. It usually presents in adults as a solitary asymptomatic skin-colored papule that is almost always on the face. We report here on an uncommon case of plexiform PEN that developed on the penis of a 43-year-old man. It was 6 mm-sized skin colored papule. Histologically, there is an encapsulated nodule with a plexiform growth pattern in the dermis and a palisading arrangement of nuclei. On immunohistochemical staining, the tumor cells of the nodule were positive for S-100 and neurofilament.
Subject(s)
Adult , Humans , Male , Dermis , Neuroma , Penis , SkinABSTRACT
The lips have important functional and esthetic facial features and the lips are used for relatively simple tasks, such as retaining oral contents, as well as for complex functions such as mastication, speech and expressing emotion. Therefore, it is esthetically and functionally critical to maintain the normal position and contour of the lips during reconstructive surgery. However, the freely movable nature of the vermilion and the cutaneous lip makes this area highly susceptible to distortion. We report here on a case of squamous cell carcinoma on the lower lip and the extensive surgical defect that resulted from total vermilionectomy and wedge resection of the lip was repaired with the tongue flap.
Subject(s)
Humans , Carcinoma, Squamous Cell , Lip , Mastication , TongueABSTRACT
Sarcoidosis is an idiopathic multisystem disease with various cutaneous presentations, and it is characterized by the presence of non-caseating granulomas in the affected organs. The specific manifestations are papules, plaques, nodules, ulcers and scar. We report here on a variant of sarcoidosis on a 71-year-old woman who showed an indurated plaque on the forearm. Her lesion's appearance was clinically similar to that of a morphea and the appearance of the lesion was unlike the commonly observed manifestations of sarcoidosis.
Subject(s)
Aged , Female , Humans , Cicatrix , Forearm , Granuloma , Sarcoidosis , Scleroderma, Localized , UlcerABSTRACT
Granuloma pyogenicum is a benign vascular tumor and usually occurs as a single lesion. But in a few instances, the development of multiple satellite lesions has been observed following excision or irritation of the primary lesion. Multiple satellite granuloma pyogenicum is a very rare variant of granuloma pyogenicum and occurs most commonly on the back, chest, or trunk, particularly in the interscapular region during childhood. We report a case of multiple granuloma pyogenicum which occurred on the unusual site of the scalp in a 70-year-old woman. The patient presented with a reddish pedunculated nodule with multiple satellite lesions on the right temporal area. The histopathologic findings of the primary and satellite lesions showed many newly formed capillaries and characteristic epidermal collarettes. The lesions were treated by surgical excision and electrodesiccation.
Subject(s)
Aged , Female , Humans , Capillaries , Granuloma, Pyogenic , Scalp , ThoraxABSTRACT
No abstract available.
ABSTRACT
A 27-year-old man had subcutaneous nodules on his left scapula and right upper arm at the site of a prior excision. On chest roentgenogram, a circumscribed mass was seen in the left up-per lung field; chest computed tomography showed an elliptical tumor around the left main bronchus. Histopathologic examination of the subcutaneous nodule and the pulmonary mass showed characteristic findings of a neurilemmoma.